On 15 November 2023, France submitted an intention to the European Chemical Agency (ECHA) for the Harmonised Classification and Labeling (CLH) of the fragrance ingredient Hexamethylindanopyran (CAS no 1222-05-5) as a reproductive toxicant and an endocrine disruptor substance. If the classification process is completed, the use of Hexamethylindanopyran in cosmetic products may be threatened.

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